Affinity DataEC50: 0.00590nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.00640nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.00920nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0103nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0114nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0117nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0130nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0139nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.114nMAssay Description:Reduction of human wild type PS1-induced amyloid beta40 level in CHO cells overexpressing human APP751 after 24 hrs by liquid phase electrochemilumin...More data for this Ligand-Target Pair
Affinity DataEC50: 0.135nMAssay Description:Reduction of human wild type PS1-induced amyloid beta42 level in CHO cells overexpressing human APP751 after 24 hrs by liquid phase electrochemilumin...More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Inhibition of gamma secretase mediated Notch1 signaling in HEK293 cells expressing truncated human Notch1 by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 42 residues) productionMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Modulation of gamma-secretase in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloid beta 42 production incubated overnig...More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs b...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as inhibition of amyloid beta 42 productionMore data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Modulation of gamma-secretase in CHO cells expressing human APP assessed as reduction in amyloid beta (1 to 42 residues) production after 24 hrs by E...More data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Modulation of gamma-secretase in CHO cells expressing human APP assessed as reduction in amyloid beta (1 to 42 residues) production after 24 hrs by E...More data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Modulation of gamma-secretase in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloid beta 42 production incubated overnig...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as reduction in amyloid beta (1 to 42) production after 60 mins by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Inhibition of gamma secretase in HEK293 cells expressing APP695 assessed as reduction in amyloid beta (1 to 40 residues) by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs by san...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Modulation of gamma-secretase in CHO cells expressing human APP assessed as reduction in amyloid beta (1 to 42 residues) production after 24 hrs by E...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs by san...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Modulation of human gamma-secretase assessed as inhibition of amyloid beta (1 to 42 residues) production by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as reduction in amyloid beta (1 to 42) production after 60 mins by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair